Heiko Enderling, Ph.D.
Assistant Professor,
Center of Cancer Systems Biology
,
Tufts University
School of Medicine
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I am a computer scientist turned mathematical biologist, and am interested in mathematical and computational models of cancer dynamics, with focus on cancer stem cells and non-stem cancer cell interactions. I use a variety of tools to explore tumor growth kinetics, but focus primarily on agent-based models to describe single cell dynamics, and partial differential equations to simulate diffusion of soluable factors used by cells grow and communicate with each other. The aim of my work is to thoroughly investigate early tumor growth and progression to understand how and why some tumors remain benign and do not advance into malignancy - a state called dormancy. If we understand the kinetics underlying tumor dormancy novel treatments might be developed that prevent aggressive growth and keep tumors in a non-clinical stage. I am very interested in Education and Outreach. I organize public evening lectures and scientific workshops.
Upcoming lectures
♦ Talk at the
9th AIMS Conference on Dynamical Systems, Differential Equations and Applications
, 7/1-5/12
♦ Invited
Guest Speaker
at MD Anderson
Odyssey Symposium
, 6/4/12
Latest
Publications
♦
Morton, …, Enderling
Non-Stem Cancer Cell Kinetics Modulate Solid Tumor Progression.
→
Theor Biol Med Model
♦
Enderling & Hahnfeldt
Cancer Stem Cells In Solid Tumors: Is 'Evading Apoptosis' A Hallmark Of Cancer?
→
Prog Biphys Mol Biol
Education & Outreach
♦
Radiation Risk: Fact and Fiction
Public Evening Lecture, 22 May
♦
Tumor Metronomics Workshop
Tufts, July 17-20
